How to use a set of characters in the javascript match method

How can I use all the following characters as a regular expression in the javascript match method and escape the characters that need to be escaped?

~!@#$%^&*()_-+={}[]|:;<>,./? and space

so that mysstring.match(REGEX) returns null only if mysstring does not contain any of the above set of characters

 "abc".match(REGEX) //should return null
 "abc@".match(REGEX) //should NOT return null (it has @)
 "ab c".match(REGEX) //should NOT return null (it has a space)
 "++abc".match(REGEX) //should NOT return null (it has +)